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KMID : 0362919930110020331
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Journal of the Korean Society for Therapeutic Radiology and Oncology
1993 Volume.11 No. 2 p.331 ~ p.335
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Treatment of Locally Advanced Pancreatic Cancer
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Kim Dae-Yong
Ha Sung-Whan
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Abstract
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From January 1981 to December 1991, forty patients with localized advanced carcinoma of the pancreas were treated at the Department of Therapeutic Radiology, Seoul National University
Hospital. The treatment protocol consisted of two split course external radiation therapy with each 2000 cGy over two weeks separated by two week rest period. Intravenous 5-fluorouracil (5-FU) was administered on the first three days of each radiotherapy course. Twenty three of these patients were treated by maintenance 5-FU or FAM (5-FU, adriamycin, mitomycin) chemotherapy. Median survival was 9 months and the 2-year survival rate was 10.0%. Good prognostic indicators were good performance status, palliative bypass surgery and tumor located in the head of pancreas.
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KEYWORD
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Carcinoma of the pancreas, Radiotherapy, Chemotherapy
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